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Silicon dioxide: the "universal pharmaceutical excipient" for pharmaceutical preparations

Medicine has been closely related to people's lives since ancient times. The production of drugs began with traditional medicine and later evolved to separate and extract natural medicines from natural substances, gradually developing and establishing an industrial production system for chemical drugs. Medicinal excipients play a crucial role in the pharmaceutical industry. Medicinal excipients refer to the excipients and additives used in the production and formulation of drugs. In addition to shaping, acting as carriers, and improving stability, they also have important functions such as solubilization, solubilization assistance, and sustained and controlled release. They are important components that may affect the quality, safety, and effectiveness of drugs. Silicon dioxide, as a widely used inorganic material, is also a very useful pharmaceutical excipient in the pharmaceutical field. The structural formula of auxiliary silica is mSiO2 · nH2O, which is a white powder with good fluidity, high purity, and no pollution. It has the characteristics of small particle size, large specific surface area, and many pores. At the same time, the silicon hydroxyl groups distributed on the surface make it have good adsorption performance. Adding medicinal excipient silica can effectively improve the quality and performance of drug formulations, especially tablets, greatly enhancing the market competitiveness of drugs. Its application in drug formulations has received increasing attention.